TM Transfection Mix
Context
Reagent-based transfection is the primary method for producing viral vectors (Lentivirus (LV) or Adeno-Associated Virus (AAV)). However, despite its significance, this critical step often lacks real-time monitoring and quality controls.
Workflow
ADVANTAGES
- Videodrop enables in-depth real-time kinetic studies to monitor the impact of various conditions (DNA concentration, ratios, media type, pH levels) on the size evolution of transfection complexes over time. Studies1 show a clear correlation between size of the formed transfection reagent/DNA complex and the transfection efficiency.
- By incorporating Videodrop into their workflows, scientists can achieve a new level of control and optimize transfection efficiency, ultimately leading to faster and more cost-effective upstream processes.
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Measuring
Size & Concentration
of Nanoparticles
Size Kinetics
and Aggregation
of Nanoparticles
