Publications internes
lipid_nanoparticle
Assessing the particle concentration of mRNA-LNP using VIDEODROP: A new metric for LNP manufacturing, optimization & standardization
Videodrop is an innovative nanoscale imaging technology. Based on the principle of interferometry, Videodrop makes it possible to measure the size and concentration of nanoparticles
lentiviral_vector
Validation of an Analytical Method for Lentivirus Physical Concentration Using Videodrop (ILM) following ICH Q2 Guidelines
Lentiviral vector (LV) clinical application involves large-scale Good Manufacturing Practice (GMP), including production purification and quality controls. By rapidly measuring the size and physical titer of nanoparticles in solution, Videodrop can be integrated in lentiviral quality control strategy.
lentiviral_vector
Fast and easy characterization of diverse viruses using Interferometric Light Microscopy (ILM)
Videodrop (ILM) is a custom microscope that uses interference phenomenon to detect the light scattered by individual nanoparticles in solution.
extracellular_vesicle
Maximizing MSC-EV Yield with Preserved Quality Using a Xeno-Free and Defined Formulation
Human mesenchymal stem cells (hMSCs) have strong therapeutic potential due to their self-renewal and multi-lineage differentiation abilities.
lentiviral_vector
IXAKA’s versatile platform for the bioproduction & characterization of lentiviral vectors
extracellular_vesicle
Videodrop : for a fast characterization of Extracellular Vesicles following a standard protocol
lipid_nanoparticle
RAPID CHARACTERISATION OF PHAGE SUSPENSIONS BY INTERFEROMETRY
Phage production’s downstream process includes a critical purification step susceptible to destabilise phage suspensions.
lentiviral_vector
Technology Evaluation: Quicker way of Lentiviral Vector Physical Titer Determination
The measure of HIV-1 p24 antigen by ELISA is a well-established method for lentivirus quantitation.
lentiviral_vector
Rapid characterization of human viruses in a droplet using Interferometric Light Microscopy (ILM) in a BSL3
Preliminary results show that ILM is not able to distinguish HIV-1 from viral particles derived from HIV-1…
Publications externes
Publication
Institution
Particle studied
Journal
Comparative and Functional Analysis of Exosomal microRNAs During Semelparous Reproduction in Ayu Fish (Plecoglossus altivelis)
Pan et al. [2025]
Pan et al. [2025]
Department of Aquatic Bioscience, Laboratory of Aquatic Molecular Biology and Biotechnology, Graduate School of Agricultural and Life Sciences The University of Tokyo Bunkyo Tokyo Japan.
extracellular-vesicles
J Extracell Biol
Rapid and Efficient Quality Control Analysis of Isolated Mitochondria by Interferometric Light Microscopy
Mozafari et al. [2025]
Mozafari et al. [2025]
Laboratoire Matière et Systèmes Complexes (MSC) Université Paris Cité, CNRS UMR 7057 45 rue des Saints-Pères 75006 Paris France.
mitochondria
bioRxiv
Harnessing hydrodynamics for high-yield production of extracellular vesicles from stem cells spheroids with specific cargo profiling
Lenoir et al. [2025]
Lenoir et al. [2025]
nstitut Curie, PSL Research University, Paris, France
extracellular-vesicles
bioRxiv
Université Paris Cité, CNRS, INSERM, Unité des Technologies Chimiques et Biologiques pour la Santé (UTCBS), Paris, 75006, France.
lipid_nanoparticles
Drug Delivery and Translational Research
When Fat Talks: How Adipose-Derived Extracellular Vesicles Fuel Breast Cancer
Cavaleri et al. [2025]
Cavaleri et al. [2025]
Translational Medicine Department, University of Ferrara, 44121 Ferrara, Italy.
extracellular-vesicles
International Journal of Molecular Sciences
Extracellular vesicle proteome unveils cathepsin B connection to Alzheimer’s disease pathogenesis
Yuyama K. et al. [2025]
Yuyama K. et al. [2025]
Lipid Biofunction Section, Faculty of Advanced Life Science, Hokkaido University, Sapporo 001-0021, Japan.
extracellular-vesicles
Brain
Characterization of Nanohybridosomes from Lipids and Spruce Homogenate Containing Extracellular Vesicles
Spasovski V. et al. [2024]
Spasovski V. et al. [2024]
University of Ljubljana, Faculty of Health Sciences, Laboratory of Clinical Biophysics, SI-1000 Ljubljana, Slovenia.
lipid_nanoparticles
International Journal of Nanomedicine
Monitoring concentration and lipid signature of plasma extracellular vesicles from HR+ metastatic breast cancer patients under CDK4/6 inhibitors treatment
Richard M. et al. [2024]
Richard M. et al. [2024]
Team SOAP, Signaling in Oncogenesis Angiogenesis and Permeability, CRCINA, Inserm, CNRS, Universite de Nantes, France
extracellular-vesicles
Journal of Extracellular Biology
Assessment of Extracellular Particles Directly in Diluted Plasma and Blood by Interferometric Light Microscopy. A Study of 613 Human and 163 Canine Samples
Korenjak B. et al. [2024]
Korenjak B. et al. [2024]
University of Ljubljana, Faculty of Health Sciences, Laboratory of Clinical Biophysics, SI-1000 Ljubljana, Slovenia.
extracellular-vesicles
Cells
Enhancing natural killer cells proliferation and cytotoxicity using imidazole-based lipid nanoparticles encapsulating interleukin-2 mRNA
Delehedde C. et al. [2024]
Delehedde C. et al. [2024]
Centre de Biophysique Moléculaire, CNRS UPR4301, 45071 Orléans Cedex 02, France.
lipid_nanoparticles
Molecular Therapy – Nucleic Acids
Anti-aging effect of extracellular vesicles from mesenchymal stromal cells on senescence-induced chondrocytes in osteoarthritis
Boulestreau J. et al [2024]
Boulestreau J. et al [2024]
IRMB, University of Montpellier, INSERM, Montpellier, France.
extracellular-vesicles
Aging
Investigating Extracellular Vesicles in Viscous Formulations: Interplay of Nanoparticle Tracking and Nanorheology via Interferometric Light Microscopy
Alexandre L. et al. [2024]
Alexandre L. et al. [2024]
Laboratoire Matière et Systèmes Complexes (MSC) Université Paris Cité, CNRS UMR 7057 45 rue des Saints-Pères 75006 Paris France.
extracellular-vesicles
Small Science
Combining antimiR-25 and cGAMP Nanocomplexes Enhances ImmuneResponses via M2 Macrophage Reprogramming
Petrovic M. et al. [2024]
Petrovic M. et al. [2024]
Institute of Pharmaceutical Sciences of Western Switzerland (ISPSO), Faculty of Science, University of Geneva, 1206 Geneva, Switzerland
nanocomplexes
Int. J. Mol. Sci.
Real-time monitoring by interferometric light microscopy of phage suspensions for personalised phage therapy
Lapras B. et al. [2024]
Lapras B. et al. [2024]
Pharmacy Department, Hospices Civils de Lyon, Hôpital E. Herriot, Plateforme FRIPHARM, 69437 Lyon, France.
phages
Scientific Reports
Exploration of microRNA Biomarkers in Blood Small Extracellular Vesicles for Enzootic Bovine Leukosis
Takada et al. [2023]
Takada et al. [2023]
Laboratory of Food and Environmental Hygiene, Cooperative Department of Veterinary Medicine, Faculty of Applied Biological Sciences, Gifu University, 1-1 Yanagido, Gifu 501-1193, Japan.
extracellular-vesicles
Microorganisms
Autologous Platelet and Extracellular Vesicle-Rich Plasma as Therapeutic Fluid: A Review
Troha V. et al. [2023]
Troha V. et al. [2023]
University of Ljubljana, Faculty of Health Sciences, Laboratory of Clinical Biophysics, SI-1000 Ljubljana, Slovenia.
extracellular-vesicles
International Journal of Molecular Sciences
University of Ljubljana, Faculty of Health Sciences, Laboratory of Clinical Biophysics, SI-1000 Ljubljana, Slovenia.
extracellular-vesicles
International Journal of Molecular Sciences
Isolating plasma extracellular vesicles from mouse blood using size-exclusion chromatography, density gradient, and ultracentrifugation
André-Grégoire G. et al. [2023]
André-Grégoire G. et al. [2023]
Team SOAP, Signaling in Oncogenesis Angiogenesis and Permeability, CRCINA, Inserm, CNRS, Universite de Nantes, France
extracellular-vesicles
STAR Protocols
Extracellular vesicles containing the I-BAR protein IRSp53 are released from the cell plasma membrane in an Arp2/3 dependent manner
Poret A.et al. [2022]
Poret A.et al. [2022]
Institut de Recherche en Infectiologie de Montpellier, UMR9004 CNRS, Montpellier University, Montpellier, France
extracellular-vesicles
Biology of the Cell
Assessment of Small Cellular Particles from Four Different Natural Sources and Liposomes by Interferometric Light Microscopy
Romolo A. et al. [2022]
Romolo A. et al. [2022]
University of Ljubljana, Faculty of Health Sciences, Laboratory of Clinical Biophysics, SI-1000 Ljubljana, Slovenia.
extracellular-vesicles
International Journal of Molecular Sciences
Inhibition of the pseudokinase MLKL alters extracellular vesicle release and reduces tumor growth in glioblastoma
Andre-Gregoire G. et al. [2022]
Andre-Gregoire G. et al. [2022]
Team SOAP, Signaling in Oncogenesis Angiogenesis and Permeability, CRCINA, Inserm, CNRS, Universite de Nantes, France
extracellular-vesicles
iScience
Highly Stable Polymer Coating on Silver Nanoparticles for Efficient Plasmonic Enhancement of Fluorescence
Kato R. et al. [2022]
Kato R. et al. [2022]
Institute of Post-LED Photonics, Tokushima University, 2-1 Minami Josanjima, Tokushima 770-8506, Japan
silver_nanoparticles
ACS Omega
Experimental Evaluation of an Interferometric Light Microscopy Particle Counter for Titering and Characterization of Virus Preparations
Turkki P. et al. [2021]
Turkki P. et al. [2021]
Kuopio Center for Gene and Cell Therapy, 70210 Kuopio, Finland
lentivirus
Viruses
The von Willebrand factor stamps plasmatic extracellular vesicles from glioblastoma patients
Sabbagh L. et al. [2021]
Sabbagh L. et al. [2021]
Team SOAP, Signaling in Oncogenesis Angiogenesis and Permeability, CRCINA, Inserm, CNRS, Universite de Nantes, France
extracellular-vesicles
Scientific Reports